"Provide data? There is no problem with this." Sun Lien immediately agreed. All he wanted was a license to use tocilizumab for the patient. As long as he had the permission, he could lean on everything else. Anyway, he did not intend to publish any articles with this treatment, so it was completely unnecessary to keep the data confidential. It would be better to say that Sun Lien even hoped that the treatment data could be disclosed every day - so that other doctors could realize the importance of precise control of the immune system earlier.

Regulating the immune system of patients with novel coronavirus is a "art" that is much more rigorous and complex than ordinary immune regulation. In the absence of effective antiviral drugs, to allow patients to recover, they must rely on the human immune system response. Only when the immune system recognizes the virus and produces enough neutralizing antibodies can it be possible to remove these viruses from the human body.

Only when the immune system is strong enough can we generate enough neutralizing antibodies before the virus causes irreversible trauma to the human body. However, a powerful immune system will constantly kill lung epithelial cells in order to control the speed at which the virus infects cells.

The complete inhibition of the immune system through hormones may cause the patient's immune system to produce neutralizing antibodies slowly. The result is that before enough antibodies are generated, the human body will be infected by large areas of lung epithelial cells and other cells containing ace2 receptors, resulting in serious organ damage and even death.

What if the immune system responds just right? Viral infection starts from the lower respiratory tract and from the edge of the lungs. As a viral infection, its properties are closer to interstitial pneumonia. Such pneumonia infections have mild carbon dioxide retention and lack warnings of increased carbon dioxide concentration, making it difficult for peripheral chemoreceptors and central chemoreceptors to respond to this and spontaneously enhance breathing.

The worst result of this...is the "silent oxygen aspiration" discovered by Director Huang Wenhui in clinical practice.

To keep patients with new coronavirus pneumonia who show symptoms alive, they must support their lives. Inhaling oxygen in the early stage, regulating the immune system response in the medium stage, and maintaining vital signs in the later stage. Only by achieving a thousand people and accurately identifying and treating each patient can the overall cure rate be improved and more patients can survive it.

The "use of tocilizumab" proposed by Sun Lien is a new attempt to regulate the immune system's response in the medium term. He hopes to use this drug to weaken the immune system's killing effect on cells, block cell storms, and maintain the speed of antibody production.

But whether it has any effect and whether it can meet the expectations of myself and Dr. Pascal...it is hard to say.

"I have another suggestion." Sun Lien said to the staff of the Health Commission after a while, "I suggest that we should carry out the dissection of the dead patients as soon as possible."

The proposal sparked a silence at the scene.

"We have already suggested this kind of thing." The Shanghai Stock Exchange leader sighed, "But suddenly suffered a major epidemic, and most of the patients who died were elderly people. It is too difficult to mobilize their families to agree to the autopsy during the Chinese New Year."

"More importantly, mobilizing the dissection now may make some families have some bad ideas." Xiangnan's team leader added, "Most of them are in a very violent mood. The sudden lockdown makes many people feel that they have been abandoned. They are mobilizing them to agree to the dissection. I am afraid that people will think that we have deliberately cured people... Director Sun, you haven't been online much recently?"

"No." Sun Lien was a little surprised at this question, "What happened online...?

"All demons and monsters are coming out." The leader of Xiangnan team shook his head, "There are a few young men in our team who like to go online. They are in a very bad mood these days. After asking, I found out that they were scolded by the demons and monsters on the Internet. "

Sun Lien doesn't understand the public opinion matters very well. However, when there is obvious problem with this kind of wind direction, you must be more careful in every move.

"I don't understand the public opinion matter." Sun Lien shook his head and decided to follow the previous working principles - to leave professional matters to professionals. "Please pay attention to this kind of matter. We should still make suggestions. We must start anatomical and pathological examination of the body of the deceased as soon as possible. This is very important for pointing out the research and treatment directions in the future."

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Some things should be done immediately. But in order to achieve better results, the implementation time nodes need to be adjusted. This kind of counterintuitive thing is in many fields. "In order to enable the immune system to better generate neutralizing antibodies to fight viruses, the immune system needs to be suppressed" is a specific example of this kind of thing.

There are many similar situations in the process of this society's operation. But... it is more difficult to convince millions or tens of millions of people than to convince the families of two or three patients. The obstacles, risks and challenges faced by relevant departments when implementing relevant decisions are by no means something that Sun Lien can understand.

It is conceivable how much political courage and decisive it will take and how many difficulties and challenges it will face.

"We will definitely coordinate the issues that leaders respond to." Before the meeting, the staff of Yunhe Municipal Health Commission tried hard to make a smile appear on his tired face, "You all have our contact numbers. If you need it, you can directly contact the staff of the Health Commission who are connected to them - it is okay to call me directly."

"Protective clothing used in the chemical industry is not unusable. At least the protective clothing we can provide to you now still meets the relevant protection standards." The responsible person of the Health Commission finally said apologetically, "Donations from all over the country are gathering for Yunhe, and the allocation of materials will take some time to resolve. Before the shortage is eased, please bear with it."

The industrial protective clothing coordinated by the Health Commission actually feels not much different from medical protective clothing. However, compared with medical protective clothing, there is a lack of a self-adhesive stick to prevent liquid from splashing into the zipper.

Sun Lien is quite optimistic personally - if there is no sticker strip, then apply it on yourself. Anyway, there is no shoe cover, so the doctors also carry it with garbage bags.

With the help of the status bar, the role that Sun Lien can play in preventing hospital infections cannot be underestimated. Through the application of the status bar in recent years, Sun Lien himself has summarized a set of ways to use the status bar to judge personal protection. If the protective clothing he wears is of sufficient level, the reminder of the status bar after entering the red zone is generally a banner-like type - concentrated on the top and right side of his sight.

If the protection level is not enough, or he takes off his mask himself, the high pathogenic warning of the status bar will be overwhelmed on his face, even so serious that it will affect his vision. Unless Sun Lien actively closes the status bar, the warning will continue to appear.

Whether the combination of industrial protective clothing and medical garbage bags can block the new coronavirus is not easy to judge by data alone, but Sun Lien will know if he put on protective clothing and went to the red zone for a while.
Chapter completed!