Chapter 188 Not the same thing (supplement 1/1 on September 5)
If myocardial ischemia ischemia and infarction, the cardiomyocytes will completely die. Adult cardiomyocytes and nerve cells are both cells with extremely poor regeneration ability. Therefore, myocardial infarction and stroke caused by cerebral nerve death. Therefore, myocardial infarction and cerebral infarction will cause almost irreversible damage. In clinical practice, the speed is the most pursued for treatment of these two diseases - the faster the reversal of myocardial infarction and cerebral infarction, the easier it is to control the range of damage. The smaller the range of damage, the easier the patient will recover later and have fewer sequelae.
It is precisely because the damage in these two places cannot be reversed clinically, so in treatment, doctors will actively intervene once they determine that there may be risks in these two areas.
With the development of modern medicine, the mortality rate of acute pancreatitis has been lowered to a point where it can be taken less seriously. However, cerebral infarction and myocardial infarction are still the first and second among Chinese residents' causes of death.
If the problem of cardiomyocytes and nerve cells can be solved, many incurable diseases may have solutions. Perhaps one day, patients suffering from diseases will be able to regain a healthy heart and a normal brain with the help of a dose.
But doctors today cannot do this. Therefore, they must do everything possible to prevent patients from having a myocardial or cerebral infarction.
Hypokalemia is a very dangerous symptom. It can induce various muscle paralysis, and even cause more serious arrhythmias and even cardiac arrest. However, hypokalemia caused by plasma replacement can be completely prevented - as long as blood potassium monitoring is strengthened and potassium is ready to be supplemented at any time.
The treatment plan was carried out by a specialist, and Sun Lien sat in his office and looked through various documents. He was still a little uneasy deep inside - Wang Ge's blood lipids rose too fast, and the amplitude was too large. Although he had heard that some patients had symptoms of blood lipids rising after receiving hormone shock, Sun Lien had never encountered this situation. What made him even more difficult to understand was why it rose so fast.
Hormone impact is not without risks. Before undergoing hormone impact treatment, family members need to sign a notice first, which lists the risks that various hormone impacts may bring.
However, the work of reviewing relevant documents was not very smooth. After the recent revision of CNKI, Sun Lien often encountered problems that good documents could not be downloaded. The information on Wanfang was not complete enough, and the papers on pubmed had some related content, but they were all paid articles - a Japanese paper around 2000, with a price of US$39.96 on the journal website.
Although doctors are very willing to exchange experiences with each other, it is obvious that capitalist journal publishing houses do not think so. The papers twenty years ago were nearly 300 yuan to download, and the papers themselves were only four pages of PDF and six pictures. This is no longer a matter of robbing... This is simply a monopoly of knowledge. Compared with this fee, a paper on CNKI is so cute that it is as harmful as a little white rabbit.
Although I was completely dissatisfied, the health of the patient was still very important. Sun Lien gritted his teeth and stomped his feet, and successfully spent the first fee he handed over to foreign journals in his life. Then he downloaded this 2000 Japanese paper.
This is a case statistics and discussion of hyperlipidemia in patients after kidney transplantation. The author has recorded the detailed situation of 129 patients with hyperlipidemia after kidney transplantation. It was also suggested that after patients treated with methylprednisolone switched to tacrolimus, the original hyperlipidemia improved significantly.
After reading the paper, Sun Lien was a little disappointed. The content of the paper was very rigorous and the argument was very detailed. But I don’t know if it was because the Japanese originally prefer a low-fat diet. The most severe hyperlipid-related patients recorded in the paper were only 282mg/dl, which was about 31.83mmol/l. This is still a distance away from Wang Ge’s blood lipid level of 50mmol/l.
Although the triglyceride levels in Japanese patients are not as fast as Wang Ge, the probability of hyperlipidemia in patients receiving 500mg/d methylprednisolone treatment is still very high. Among the 947 patients recorded in the paper, 129 of the 947 patients recorded in the paper have increased triglycerides to varying degrees. The incidence of hyperlipidemia of about 13% seems to be fine.
"What are you doing?" Yuan Ping'an wandered to Sun Lien, stretched his neck to look at the computer screen, and then asked in surprise, "Look up the documents?"
"I'm a little worried about Wang Ge's blood lipid level." Sun Lien sighed, "It's just the next day when the hormone impacts, and his triglycerides are about 50..."
"Is there anything worth worrying about this...?" Yuan Ping'an asked in confusion after thinking for a while, "After receiving hormone shock treatment, blood lipid rise is a normal side effect, right?"
"Yes." Sun Lien nodded, "But from normal, it suddenly soared to 50, and this level is too high. I'm worried if there are other factors that lead to such a high triglyceride level, so check the literature and take a look."
Yuan Ping'an frowned and thought for a while, then continued to shake his head, "I really don't realize that there is anything special about this situation - I have seen more exaggerated increase in the collaboration before. After receiving hormone shock treatment, this is normal..." He shook his head and continued to ask, "Forget it, it doesn't matter what I think, have you found any related content?"
"No." Sun Lien sighed, "I have never seen such a high increase before, so I checked it out... and it cost more than 200 yuan."
"Is there any more money?" Yuan Ping'an was even more shocked, "What kind of documents did you use to look up? pubmed?"
"It's pubmed." Sun Lien specially opened his payment interface and record, "The full text needs to be downloaded and paid."
Yuan Ping'an looked at Sun Lien as if he was looking at a monster, "You really give it?" After pausing for a few seconds, he suddenly laughed, "That's right, you probably haven't done much scientific research before, and you haven't seen many babies." Speaking of this, Yuan Ping'an pushed Sun Lien away from the front of the computer without hesitation, and then began to enter a URL on the keyboard with both hands, "Come on, I'll show you a baby."
This feeling...a bit like the days I used to be in my college dormitory.
"After you search for the documents you need to find from pubmed, write down the pmid number, or this doi number," Yuan Ping'an handed over how Sun Lien how to bypass the knowledge barrier of capitalism, "and then just enter it on this website..."
"What are you doing?" Xu Yourong didn't know when he arrived in the office, but the atmosphere of the "men's club" at Sun Lien's desk was so strong that Xu Yourong himself was reluctant to get close. "The information department is staring at the Internet access content in our hospital. Don't say that I didn't remind you, if you look back and criticize me, everyone will not look good."
"You must have used this website." Yuan Ping'an said without even replying, "Isn't it just a look at P and Hub? Can the Information Department eat me?"
Xu Yourong was silent for a long time, "I remember this website that cannot be accessed in China..."
Yuan Ping'an suddenly raised his head. He glanced at Xu Yourong, who had an abnormal expression, and then coughed, "I'm talking about pubmed and sci-hub."
Xu Yourong left the office without saying a word, and Yuan Ping'an continued to look down at the screen, as if nothing had happened.
Sun Lien lowered his head and wrote down the two websites that Yuan Ping'an mentioned. After a while, he asked, "What you two said just now... isn't the same thing?"
Chapter completed!