Chapter 38 Taking Poison
In fact, Li Heng knew that he had already encountered a resource crisis when he was studying the information sent by "Liu Yinzhen".
This means that the resources at his disposal are no longer enough to support some of his subsequent experiments and practices.
It's not a matter of money, but that as an independent private "researcher", the things he can currently obtain are his personal limits.
"Liu Yinzhen" mentioned in the information that the subsequent experimental methods would require several special experimental reagents and special drugs, but Li Heng did not have the means to obtain these.
However, "Liu Yinzhen" still believed that he was a doctoral candidate in a biological laboratory of Northwestern University, so naturally he felt that it was possible to obtain these things by applying to the project leader or supervisor.
So Li Heng could only sigh with excitement when looking at many plans. He even thought about it, why don't he take some risks and go to special channels to get them?
But he didn't do it in the end. The risk was small and the risk was big.
Later, he decided to take another path, which was to find similar substances as substitutes, as much as possible within his normal reach.
Among them, the secretions of natural organisms are a good choice.
There are all kinds of strange creatures in nature. Each of their bodies is a completely different natural chemical factory. All kinds of strange chemicals are synthesized in their organs and glands. Many of them are even used by human chemical industries.
It cannot be copied so far.
Finding substances with similar chemical properties and using them to replace the pharmaceutical drugs mentioned in "Liu Yiyi Zhen" is something Li Heng has been considering.
When it came to Brother Toad, Li Heng gave it a back rub service to collect the venom secreted by the knots on its back.
The five poisons have been used as medicine since ancient times.
The ferocious and terrifying black-striped viper, which was originally a top predator, was now held in Li Heng's hand as if it were a large earthworm and had no temper.
Then came the next "brother". Li Heng made a closed container in the shape of a small mouse out of plastic and threw it into the glass container of the centipede. As soon as he put it in, the poor "little mouse" was killed by the centipede brother.
After saying hello, he frantically stung him with his pair of poisonous pincers, thinking it was food brought in.
And there have been some suggestions before. For example, the neuroreceptor agent similar to methylamine mentioned in the data can be replaced by the product of filtration and hydrolysis of separated snake venom protein. The two have similar properties, and they can also target epithelial tissue.
Astragalus, which regulates cell permeability, can be replaced by the acidic secretions of some insects and arthropods. The sodium potassium triacylphosphate solution used in the respiratory tract is obtained by decomposing specific plant fibers using the bacterial flora hosted by certain reptiles.
Approximate solution...
The main components of snake venom are various venom proteins and polypeptidases. If broken down, the various components are very complex and may range from dozens to hundreds. However, according to the classification of functions, they can be roughly divided into two categories: blood circulation toxins and neurotoxins.
.
He took the gecko's urine, and then used his own medium to cultivate the bacteria. After the bacterial colony multiplied to a certain scale, he gradually added other substances and various plant fibers.
The dienol compounds in toad toxins have a biochemical mechanism that directly acts on the cardiovascular and cerebrovascular systems. It can also affect human structures such as nerves, myocardium, respiratory tract and even digestive system. Its scope of action even exceeds that of snake venom and insect venom. In Li Heng's plan
occupies the core drug role.
As for toads, this ugly thing is more terrifying than it is scary. Many people think that this thing is not very poisonous. At most, it makes the skin itchy and allergic and makes some big bumps. The deterrent effect is far less than that of poisonous snakes, centipedes, scorpions, etc.
Just a terrifying creature.
After squeezing it like a cow for several minutes, and after confirming that nothing more could be squeezed out, Li Heng casually put the long snake back into the glass container.
So he has been looking for a "big guy" that is big enough, strong enough, and powerful enough to produce the chemicals he needs!
Fortunately, God favored them, and now, these "good friends" are obediently lying down in the mansion Li Heng bought for them, and they are entertained with delicious food and drinks.
Several very important chemical substances cannot obtain sufficient medicinal effects just by relying on ordinary organisms. The concentration of biomass they secrete cannot reach the level required by Li Heng, and even if it is purified, it is very difficult.
Li Heng also did a lot of investigations like this, but he soon discovered that most creatures could not meet their ideal needs.
Each time it is stung, its venom penetrates into the holes inside the plastic and is stored in the storage ball inside.
The black snake that was originally full of murderous aura was now squeaking, as if it had been drained of all its energy, staggering around inside.
The last section of the scorpion tail was stored in a dehumidification cabinet and dehydrated and air-dried.
As for the gecko itself, it is not poisonous, but there is a special type of bacteria in its urine. Those bacteria can produce toxic substances, but these bacteria have other uses for Li Heng.
Centipede toxin is a complex acidic fusion substance liquid, including hemolytic protein, histamine, lipids, etc. Among them, hemolytic protein and histamine can significantly change the cell permeability, and can be precipitated using Rockwell's preparation method.
Heavy acid solution to obtain the blood medicine Li Heng needs.
The five poisonous things were killed and the remaining corpses were used as medicinal materials, either by grinding, soaking, or boiling, but the ancient methods were too crude.
But this doesn't mean living and eating for free. After enjoying it, all that's left is to work for yourself.
Black-striped adder venom is a neurotoxin that affects the binding of neurotransmitters. The toxic concentration of the snake venom collected by Li Heng is far higher than that of ordinary snake venom of the same kind. The trans-polymer chain polypeptide generated after the hydrolysis reaction is passed through a centrifuge.
can be separated.
Li Heng's method of utilization is a combination of modern biochemical medicine, starting from the microscopic components and using their respective products in the most refined way to maximize their use, rather than smelting them all in one pot and allowing those complex and diverse compounds to be absorbed in the body.
All kinds of uncontrollable metaplastic reactions are taking place.
As for the black scorpion, which was bigger than a palm, he directly chopped off the poisonous sting in the scorpion's tail. After all, this was the only one-time use and there was no need to repeatedly remove the poison.
The first one to bear the brunt was the black-striped viper as thick as a child's arm. The moment he opened the glass box cover, it suddenly jumped out. It was obvious that it had been waiting for a long time to give Li Heng a hard blow!
But Li Heng didn't even raise his eyelids. He pinched it with his backhand. The nearly two-meter-long snake body was wrapped around his arm in two twists, like a lifeless hemp rope. Then he pinched it with his fingers slightly, and it was gone.
The snake's mouth opened, and two bright fangs were pressed against the wall of the beaker. Strands of translucent snake venom protein liquid overflowed and were collected in the beaker.
But this is definitely an underestimate. Toads are no less toxic than any other poison. Some people even think that toads are the first of the five poisons!
"If I succeed this time, I can break away from my current 'drug taking' career and use the power of the five poisons to reshape the mechanism cycle of the inner world and the earth, and no longer have to rely on energy-efficient substances."
Amidst the buzzing of the centrifuge, Li Heng looked hopefully at the increasingly full test tubes and the five "brothers" who were working there.
"However, before I try this "Five Poison Magic Medicine", I have to settle some common things first."
His eyes turned to the village, to an old dilapidated bungalow, which was the only person he could still regard as a relative.
Chapter completed!