Looking at the virtual demonstration animation in the air above Wu Hao's head, the guests sitting at the front of the guest seats couldn't help but communicate with each other.
"Mr. Yun, what do you think?" An old man in his fifties and almost sixty years old wearing a white shirt smiled at an old man next to him with gray hair, but still energetic, about seventy years old and in good shape.
asked.
This gray-haired old man is none other than Academician Yun Zhihong, one of the country's authoritative experts in digestive sciences.
He glanced at the confident and sunny young man standing on the stage and smiled: "It's interesting. Using super phages to devour harmful bacteria is not something we haven't done before. In fact, many countries are also doing it. And
The kid on the stage was able to produce such results in such a short period of time, which is really impressive. However, the development of new drugs is a very complicated matter. There are many drugs that were very good in the first and second phase of clinical trials, but in the end
All failed."
"You don't like it?" the old man in the white shirt said in surprise. He is the leader of gastroenterology in a well-known hospital in China and one of the very famous experts. This time he was also invited to Anxi to participate in this event.
press conference. Their hospital is also one of the clinical trial sites for this new drug, so it is quite familiar with this new drug.
Yun Zhihong shook his head, then smiled slightly and said: "It's not that I'm not optimistic, but I think this guy is a little too anxious. The development cycle of new drugs is usually relatively long, and the shortest one usually takes four to five years.
Six years, this guy was a little too anxious to compress the time into three years.
However, judging from the data and information currently displayed, the prospect of this drug is still very good. Xiao Wang, I remember that your hospital is also the clinical trial unit of this new drug, and you yourself should also be involved in the clinical treatment of this new drug.
Bar.
Based on your personal professional judgment, how do you think this drug performs clinically?"
Facing Yun Zhihong's inquiry, the old man in the white shirt thought for a moment, and then affirmed: "Our hospital has participated in the first and second phase clinical trials of this drug. A total of more than 600 patients have participated in the first and second phase clinical trials.
It is undergoing trial treatment. As far as the efficacy of this new drug is concerned, it is very good. It can be said that it cannot be better.
You also know that the current treatment method for Helicobacter pylori in the stomach basically adopts triple or quadruple medication used by international counterparts. Basically, the treatment effect is very significant. But there are also disadvantages, that is, the treatment cycle is long.
It can last from a few weeks to a few months. There may even be a resurgence of the infection after stopping the medication, and there may be repeated infections.
Triple quadruple therapy uses a huge amount of drugs, and the toxic and side effects will accumulate in the body, causing harm to the body. Especially for critically ill patients with other diseases, triple quadruple therapy may not be so suitable.
.
As for this drug, there are basically no toxic or side effects. What it contains is super phage. This virus only targets Helicobacter pylori in the stomach. After killing all Helicobacter pylori in the stomach, it then divides and reproduces.
The super phage will quickly lose activity due to lack of 'food' and eventually die and be eliminated from the body.
Therefore, it can be used in the treatment of some critically ill patients and patients with other underlying conditions.
In clinical trials, we have used this drug to cure several patients suffering from other critical illnesses and successfully restored their gastrointestinal function, which ultimately enabled them to turn around and be discharged from the hospital.
In addition, its therapeutic effect on Helicobacter pylori in the stomach is also very obvious. Basically, the entire treatment process can be controlled within a week. The effect is already very obvious after one day of taking the medicine, and the daily data changes after that are very obvious.
Yes. It takes about three to four days to clear more than 98% of the Helicobacter pylori in the stomach. After intensive treatment in the next two days, the C13 and C14 tests of these patients have become completely normal."
"As for side effects, are there no findings?" Yun Zhihong nodded and then asked.
The old man in the white shirt shook his head: "From our current monitoring, we have not found any side effects. The only two patients with adverse reactions developed diarrhea after taking the medicine. However, these two patients had severe gastrointestinal diseases and
It cannot be shown that their diarrhea is directly related to the new drug.
We have done a lot of clinical trials of this new drug over the years, and we have very rich experience in this area and a very strict supervision process. Therefore, if patients have any adverse reactions, we will know it as soon as possible, but from now on
Judging from the test results, we did not issue it directly."
Yun Zhihong nodded, then looked at Wu Hao who was preaching on the stage, and said with a smile: "The super phage itself is a virus, so compared to ordinary chemical molecular drugs, it has no toxic or side effects, which is normal.
But this does not mean that it is absolutely safe. Since it is a virus, it may mutate and may affect or even harm the entire human system.
In particular, this is a super phage that has been artificially cultivated and modified, so I am worried that its genetic structure may not be so stable and prone to mutation. Once it mutates into a harmful virus, according to the characteristics of this super phage, the result is really
terrible."
Yun Zhihong expressed his concerns. It was not that he was not optimistic about this new drug, but he was worried about the potential risks it would bring. Especially regarding this kind of viral drug, one should be even more cautious.
After hearing Yun Zhihong's words, the old man in the white shirt nodded in agreement. Indeed, bacterial drugs should be treated with caution. But after hearing the meaning of Yun Zhihong's words, it seems that something needs to be done.
"Do you want to..."
Facing the hesitant old man in a white shirt, Yun Zhihong smiled and shook his head: "This is just my personal worry. Judging from the performance of this drug, it is still very good. If it can pass the third phase
Clinical trials, as well as the new drug marketing approval process of relevant departments, so why should I speak out against it.
For those of us with dry digestion, the emergence of such a new drug is definitely a great blessing for our entire discipline. With it, some very difficult diseases in the past can be well solved.
Moreover, its low or zero side effects can help humans completely remove and eliminate Helicobacter pylori in the stomach and reduce the induction of gastric diseases.
From this aspect, I am very much looking forward to this new drug."
