"This telomerase is undetectable in normal human cells, but scientists have found that it is highly active in some malignant tumor cells such as ovarian cancer, lymphoma, acute leukemia, breast cancer, colon cancer, lung cancer, etc.
Telomerase is very interesting.
"Therefore, scientists are studying whether this telomerase can be used as a target for tumor therapy to treat these malignant tumor diseases, which has broad research prospects.
"In addition, there are many factors that affect aging, such as genetic factors. Affected by one's own reasons and external factors, the integrity and stability of the human body's DNA may be affected, resulting in mutations, translocations, chromosome gains and losses, etc.
Problems, these all affect human aging and disease, leading to death.
"In addition, problems such as loss of protein balance, dysregulated nutrient sensing, mitochondrial dysfunction, cellular senescence, stem cell failure, and chronic inflammation also affect human aging and lifespan. However, these are consequences, while telomere depletion is the antecedent.
, is also the main reason. After excluding the influence of some external factors, telomere depletion can be said to be the decisive factor affecting human aging and lifespan.
"So how to solve this problem, delay the depletion of telomeres, or even supplement the loss of telomeres, this is also a topic that scientists have been studying. Our biomedical research team has been conducting research in this area and has achieved some results.
, report to everyone through this press conference.”
coming!
After hearing Wu Hao's words, everyone couldn't help but get excited. They thought this conference would be relatively "bland". Although the previous technical products were already very good, everyone always felt that there was something missing, and now
The wait is finally here.
Not only the guests at the scene, but also the media reporters behind them were also excited. They originally thought that this press conference would be like this, but they didn't expect that there would be something serious. They finally got what they wanted.
Not only the scene, but also the Internet was exploded by Wu Hao's news. It quickly began to spread and ferment, and the number of viewers in major live broadcast rooms also increased significantly.
"Our biomedical research team found that there are many factors that affect the rate of telomere consumption, or there are many factors that affect telomeres. These factors can affect the shortening of telomeres, and they can also cause them to grow. Yes, growth.
"We found that the substances consumed by telomeres can actually be replenished, and only require some special methods. In other words, we can control the consumption of telomeres through these special methods, greatly slow down their consumption rate, and prolong their consumption.
It consumes time. At the same time, we can also stimulate the growth of telomeres in this special way.
"In this way, we can increase the number of divisions of human cells, thereby extending the natural lifespan of humans. At the same time, due to the consumption of telomeres, various functions of the human body will continue to age and deteriorate. This is why with age
As we grow older, we may feel that our body functions are not as good as when we were young.
"As long as we control the consumption rate of telomeres, we can delay aging. By stimulating the growth of telomeres, we can gradually restore youthfulness to an already aging body and extend people's natural lifespan."
At this point, Wu Hao smiled and said to the audience: "We will see you in the latest issue of Nature magazine about the relevant scientific research results in this area, and you are welcome to read them at that time."
Wu Hao continued: "Now that scientific research results have been obtained, how to translate them into applications is a major problem facing our biomedical project research team.
"First of all, we need to conduct biological experiments to verify the reliability and safety of these technologies, especially using our method to slow down the rate of telomere consumption and promote telomere growth, whether it will cause harm to the human body, and whether there are risks and uncertainties
And other issues.
"Therefore, we have been experimenting with this technology for a long time and have achieved some gratifying results. Please take a look at the content on the screen."
"These mice on the screen are the subjects of our relevant technical experiments. The fifty mice in the upper row are naturally growing healthy mice and are used as reference objects; while the fifty mice in the lower row are
These are experimental mice that we used special methods to slow down the rate of telomere consumption.
"Generally, the lifespan of healthy mice in the natural environment is about eighteen to twenty months, and rarely live to thirty months.
"We conducted experiments related to controlling the rate of telomere depletion on these fifty experimental mice, observed them for two and a half years, and recorded the entire experimental process in detail.
"As you can see, the fifty white mice that were first tested were affected by the experiment and would suffer from some symptoms such as poor mental health and reduced diet. However, as time went by, they gradually returned to their normal state.
"Subsequently, we carefully cared for the fifty pairs of mice used in the experiment, and found that the fifty healthy mice that were not tested would gradually die over time. One year later, only thirty-seven were left.
; Two years later, only twelve were left; two and a half years later, only three were left, and now there are zero.
"After the experiment, forty-six of the white mice were left after one year, forty after two years, and by the end of the experiment, thirty-seven were left. Now there are still three.
Fifteen.
"Five of them died due to unnatural factors, that is to say, in two and a half years, only eight mice died due to various diseases and uncertain factors, which is far fewer than these mice that grew naturally.
"We conducted a total of ten groups of such experimental control groups, and the test results were similar. The number of mice at the end of the experiment was basically maintained at about forty. This shows that our method can basically achieve the experimental goal, and it is useful for controlling delayed telomeres.
It has a certain inhibitory effect on the consumption speed.”
After giving everyone some time to react and digest, Wu Hao continued: "Through these experimental results, we found that the method of slowing down the consumption of telomeres has a significant effect on extending the lifespan of mice. This provides us with further research on the relationship between telomeres and lifespan.
provides important clues to the relationship between them.”
Wu Hao pointed to the data chart on the screen and continued to explain: "We conducted detailed physiological indicators testing on the experimental mice and found that the experimental mice that slowed down the consumption of telomeres performed better in aspects such as blood circulation, immune function and organ health.
They are in better condition and are healthier and more energetic than naturally grown mice.
"This research not only has a positive impact on mice, but is also of great significance to human health and lifespan extension. Our research results provide new ideas and directions for exploring ways to extend human lifespan."