Emperor Napoleon III fell ill, and on the day he won the Legislative Council election, he still suffered from his old problem - bladder stones.
On the advice of the doctor, he performed the operation. During the operation, as usual, Queen Eugenie was the regent. For Eugenie, this was not a good job. She preferred to accompany her young son instead of dealing with government affairs.
But this does not mean that she does not care about Emperor Napoleon III. She even wrote to Zhu Xianhai specifically to ask if Ming Dynasty had suitable medicines - after all, Ming Dynasty's medicines are well known to be developed.
Emperor Zhu Da was of course confused about this. Although Imperial Pharmaceutical Company has long become a world-famous pharmaceutical company with drugs such as Lixazone, aspirin, and berberine, those drugs have no effect on bladder stones.
effect.
"So, we don't have any medicine to treat bladder stones?"
Emperor Zhu Da frowned.
"Yes, Your Majesty,"
Sun Yeli thought for a while and said.
"Perhaps, we can think of some ways to use herbal medicine. For example, money grass and Gallus gallus gallus domesticus both have certain curative effects."
Although Sun Yeli studied chemistry when he was studying abroad, it did not prevent him from studying traditional medicine. He has been conducting drug extraction experiments in the laboratory of Imperial Pharmaceuticals, and has also developed several new drugs based on traditional herbal medicines.
In today's Ming Dynasty, there is no so-called "Chinese medicine" and "Western medicine". The former may also be turned into a new type of medicine through chemical extraction of active ingredients.
"They won't believe that."
Zhu Xianhai waved his hand directly and then asked.
"How is the company's recent drug research and development?"
Although Nanhua started his business by relying on drugs, in the past few years, Emperor Zhu Da did not pay much attention to drug research and development. After all, as an emperor, he could not lie down in the laboratory. At most, he would only give some
Technical support - that is, buying some books on drug synthesis and the like from the Life Mall.
However, even so, Imperial Pharmaceuticals has not launched a "new special drug" for several years. After all, the technical conditions are here. The so-called Western medicine actually starts from the extraction of plant alkaloids and herbal medicines, and then progresses to alkaloids.
Semi-synthesis, then total chemical synthesis, until drug discovery based on design, this process lasted for up to a hundred years.
Even if Emperor Zhu Da could provide some technical information or directional information, it would not make much sense. After all, some technologies require time to accumulate.
"Your Majesty, this year the company has made some attempts based on traditional medicines. Currently, we have launched more than two hundred new medicines..."
When Sun Yeli mentioned two hundred new medicines, Emperor Zhu Da was secretly stunned. The speed was too fast. According to the standards of later generations, most of the medicines were Chinese patent medicines. How effective were the medicines?
Emperor Zhu Da couldn't explain clearly, but what is certain is that European and American countries welcome Imperial Pharmaceutical's proprietary Chinese medicines with both hands. After all, in this era of relying on metaphysics to treat diseases, those proprietary Chinese medicines with indications of indications are simply magical.
medicine.
As for adverse reactions, people don't care at all these days. Besides, there are generations of European and American people who have been experimenting with them. Sooner or later, they will figure out what adverse reactions there will be. As for whether people will die in the process, taking medicine... can they not die?
person?
The most important thing is of course making money - last year, Daming's drug exports reached an astonishing 37 million yuan!
The profits are naturally very considerable.
"...these new drugs have a wide range of uses and have good therapeutic effects. For example, the licorice tablets launched this year are a drug with good antitussive, expectorant and antiasthmatic effects. According to feedback from the domestic and European and American markets, in addition to treating filial piety,
In addition to having a certain effect on asthma, it even has a certain therapeutic effect on tuberculosis."
When Sun Yeli mentioned licorice tablets like a treasure, Emperor Zhu directly waved his hand and said.
"It's just temporarily covering up the disease...wait, tuberculosis?"
Emperor Zhu Da was stunned when he only finished speaking half of his words.
Tuberculosis!
This disease is a serious disease. In this era, it is not only an incurable disease! It is also an infectious disease with an extremely large number of patients.
After the industrial revolution, the population surge and abnormal urbanization caused by industrialization became a hotbed for the spread of tuberculosis. Due to the poor working environment, pollution caused by industrialization, low immunity caused by malnutrition and the scarcity of public health resources,
The infection rate and death rate of tuberculosis have increased significantly. In 1799, one in every 3.8 deaths in the UK died of tuberculosis. From 1851 to 1910, tuberculosis caused about 4 million deaths in England and Wales - accounting for 10% of all deaths.
13%!
Not to mention that tuberculosis is rampant in Europe, there are also many tuberculosis patients here in Ming Dynasty. Even before immigrants board the ship, they need to undergo a physical examination, but there are still inevitable tuberculosis patients among them, and there are many immigrants on the ship.
Infected with tuberculosis.
This disease is a terminal illness!
Not only is it a terminal disease, but it is also a terminal disease with many patients!
"Maybe……"
A drug - isoniazid - flashed across Emperor Zhu Da's mind. The reason why he knew about this drug was entirely because isoniazid became a "poisonous dog miracle drug" and caused an uproar in the news. It was through that
News, Zhu Xianhai learned that isoniazid is a drug for treating tuberculosis.
Emperor Zhu Da didn't care whether it was a magical drug that poisoned dogs. What he cared about was that this drug was invented in 1952 and was very effective in treating tuberculosis.
More importantly, Emperor Zhu Da knew the synthesis route of this medicine!
"Obtained by the condensation of isonicotinic acid and hydrazine hydrate. Dissolve isonicotinic acid in hydrazine hydrate, add the crude mother liquor from the previous batch, and distill under reduced pressure..."
Recalling the preparation process that he saw on the Internet, Emperor Zhu Da couldn't help but thank him in his heart for the "poisonous dog incident" that had caused a lot of controversy. If it hadn't caused a lot of controversy, he wouldn't have noticed the news or paid attention.
to its preparation process.
This process is not complicated!
Not only is it uncomplicated, it is also very simple. Once this drug is synthesized, Emperor Zhu Da does not know whether someone will use isoniazid to poison dogs, but this is definitely a blue ocean!
There are tens of millions of tuberculosis patients in various countries around the world. With isonicotinic acid, those patients' diseases can be cured. Of course, the more important thing is money!
A big market with tens of millions of people, no matter what, it has to be a big market of hundreds of millions, or even billions!
For Ming Dynasty, which is currently developing rapidly, having such a huge and high-profit industry will definitely stimulate the economic and industrial development of Ming Dynasty.
After all, the basis for developing industry and commerce is money.
In the Nanhua era, Nanhua didn’t just rely on pharmaceuticals to get started!
Now we have arrived in Daming.
The profits brought by this drug can even support the further industrialization of daimyo. After all, this is a large market worth hundreds of millions of yuan every year.
Such a huge market, such huge profits. It has been ignored for such a long time.
Even if you stand on the shoulders of giants, there will be times when things get dark.
"We can't delay any longer, we have to act quickly."
For a moment, Emperor Zhu Da felt a little uneasy...
The only premise is that there are still some technical issues that need to be overcome, such as certain raw materials that need to be further "invented". After all, some raw materials for synthetic drugs have not been invented yet.