In the homeland of otherworldly souls, new drugs generally go through many steps to be launched on the market.
Experimenters need to identify a drug target from a vast number of options, and then search for compounds that can act on this target. The source may be long-term research and development, or it may be due to an unrelated experiment.
After completing the difficult or European development, the experimenters proved at the cellular level and animal experiments that the drug can indeed solve the disease, and will not solve the patient at the same time. After a lot of lengthy but necessary ethical approvals, it may be able to enter the market.
Clinical trials, from experimental animals to humans.
In the early barbaric development era when security awareness and conditions were not very adequate, developers would occasionally use themselves as replacements. Of course, this is not recommended.
After passing the approval, the drug enters the well-known three-phase clinical stage. The first phase tests the pharmacokinetics of the drug in the human body and clarifies the safe dose; the second phase initially evaluates the effectiveness and safety of the drug to provide reference for subsequent trials.
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In the third phase, the trial will be expanded to further verify the effectiveness and safety through a large-sample double-blind randomized controlled trial. It needs to be carried out by multiple medical centers under the strict supervision of doctors.
Only a few lucky people can spend years going through these steps and finally be approved for production and marketing. They can benefit one party as a patient savior, or they can harm one party as a fish that slips through the net.
Although on a longer time scale, there will always be fish that slip through the net in various senses, this is still an important line of defense to ensure life safety.
In the current North, the situation is much simpler.
As long as a person who claims to be a doctor comes up with a new drug through research and development methods including but not limited to personal thinking, literature research, pharmacological derivation, taking supplements according to what he eats, and dreams from gods and men, etc., then he can submit it to the doctor on the same day.
Colleagues in the industry, friends and family, and ignorant patients announced the good news.
This drug will then enter markets of different sizes and be applied to different groups of people depending on its personal influence.
The effects and consequences of drugs, as well as the resulting social problems, are left to the discretion of doctors and patients.
Digitalis is a drug whose toxic dose is relatively close to its effective dose. It is a drug that needs to be used with diagnostic capabilities. Unlike ether, it is purely natural and requires almost no threshold for preparation.
At present, most doctors with a similar level to David only prescribe medicine for edema. However, in addition to heart failure, which can cause edema, there are also nephrogenic edema, nutritional edema, allergies and inflammation that can also cause edema.
If he thinks that a drug should be effective but is actually ineffective, taking David as an example, his first reaction will definitely not be that the diagnosis is wrong, but that he will increase the dosage of the drug.
If they dare to reveal the ingredients today, they will be able to create a large number of cases of digitalis poisoning the next day. Instead of thinking about how to cure it, it is better to go directly to the priest to learn about medieval hospice care, which is more cost-effective and reduces doctor-patient conflicts.
For the sake of people and himself, Kraft felt that it should be tried on a small scale first, and then introduced in conjunction with the diagnostic criteria for heart failure.
Therefore, there were only rumors among individual patients that there was some kind of special medicine for edema in that special clinic. This was nothing compared to "tuberculosis treatment" and did not attract much attention.
...
...
Green raised his forehead, which was pressed red by the folds of his sleeves, and found that the light of the candle on the candlestick was already weak, and the flames were falling along the snake-shaped twisted black line, and were about to be submerged into the mass of melted wax.
There are several documents spread out on the table, which were just delivered today. This month's expense accounts, pensions for martyred monks, daily reports, and official letters from the bishops' conference.
He didn't seem to have finished processing everything before falling asleep.
He had already read the last one, which was given to him personally by his immediate superior. His attitude changed slightly from before, saying that the matter was over, and suggested that he take some rest before devoting himself to other matters.
A few days have passed. Unexpectedly but reasonably, the bishops' conference has not made any substantive punishment for the casualties. It has only issued written accusations, banned participants from talking about related topics, restricted the scope of movement for two weeks, and went to the hospital at the same time every day.
The small prayer hall reflects under the gaze of the Father.
It's more of a comfort than a punishment.
Looking at this development trend, things are really going to pass like this, stranded calmly in the tributaries of time, left far behind, just like those things that happened in the past.
From a personal point of view, I inevitably feel a little unwilling to do so, but rationally speaking, Kraft's attitude is right. Letting those things continue to be buried deep in the ground and not touching them again is the best way to deal with them.
As for himself, now he needs to tie up the matter, arrange the pension work, explain to the families of the deceased that they dedicated themselves to the Father, and go to the perfect country first.
Every time he said these words, he felt very awkward, and the thoughts of those who firmly believed in embarking on the path of "ending all pain", and the smiles cast on their faces, repeatedly appeared in his mind.
"The paranoid pursuit of metaphysical concepts, and the expectation that a supreme external force will intervene to achieve it..." This experience gave rise to a deeper feeling in his heart, and he felt that he should write it down, "I have never failed to achieve it with the intervention of a supreme external force..."
It ends tragically.”
Except for a few documents on the table, there was no extra paper at the moment, and not even a bookmark could be found.
"Wardin, can you get me some more paper?" Green called out the door and continued to open the report sent by the monk. This was just delivered by Wattin, and he was still outside helping to sort out the other documents.
Since the attack on the clinic, the heretics have not organized any activities that can be noticed. Probably their main members are, as Kraft judged, entering the other world and never coming back. Naturally
Toward self-destruction, no need to pay much attention.
However, all the sentries around the clinic have not been removed yet, so part of this report was sent by them. There is no new discovery, and the main content is just one thing.
[A professor has recently started using a new drug, and it is said that the effect is remarkable]
Green put his cold hands on his face, trying to wake up his brain that was not yet fully awake. How could it be such a coincidence that a new drug was developed within a few days of returning with the sample?
No, you have to go and see.
"Wardin, can you come here?" The priest read the next two sentences. They were all anecdotes collected from the patients. They were invalid information and someone had to go and look at them.
"Wardin...?"
Green pushed the chair away and looked at the half-open door. This was the second time he called Wadin. A strange feeling arose, as if the pebbles thrown into the pool failed to cause normal ripples and there was no sound of falling into the water.
.
Maybe he didn't want to be disturbed and left early?
"..." A voice, a vague voice.
Before I could distinguish its location, it disappeared, evaporating like water mist, as if it had never appeared. It was not Wading, and its voice was very young, like a child who had not yet reached the stage of voice change.
"Who? Are you still out so late?" There are indeed children in the church, but they are all in the choir, have fixed residences, are strictly controlled, and rarely wander to other places.
If he got lost, he'd better send the person back as soon as possible, otherwise the little guy would be reprimanded lightly.
Taking a step toward the door, the strangeness became more obvious, and turned into a sense of disobedience that could not be ignored. Wading should not leave without closing the door.
"..." A breath-like air seeped out from the cracks in the floor tiles. It was old, shriveled, and blew into the ears.
Fear made the heart tighten, the spirit tense, and the force subconsciously exerted force. However, as soon as the feet were empty, the floor shattered and pulled away, and everything around him flew away quickly, falling into the boundless thick darkness. The feeling of weightlessness made the body tremble instinctively.
.
The fall only lasted for a moment, and a feeling of support appeared under the folded arms.
Green raised his head, with the stinging pain from the folds of his sleeves still lingering on his forehead. The candle flame flickered in front of his sleepy eyes. The dripping drops blew into the room with the night wind, wetting the papers on the table and falling on his face.