In the next half month, in addition to regular lectures, Grete plunged into animal experiments. He and Matthew each had a beak protective suit. As for Bernard, he had to use bubble gauze masks to help make some
The matter of carrying and lifting——
By the way, does the barbarian have a physical constitution of 2? Or is it a toughness of 2? In short, Gretel feels that the most that can cure his illness is to make Bernard sneeze...
All in all, the safety of the experimenters is temporarily reassuring. Gretel designed the process as carefully as possible, and with the help of Pastor Matthew, began to conduct animal experiments:
All healthy animals are placed in one cage per cage. Pay attention to the placement and air flow direction, and try to prevent the air between cages from flowing to each other to avoid cross-infection of experimental animals.
The soil rises up to form walls and partition cages);
One-third of the experimental animals were placed in each cage, and one bat was placed in each cage to observe whether the experimental animals would be infected if they lived with the bats;
One-third of the experimental animals were treated in different ways: adding bat urine, bat guano, bat saliva, dust wiped off the bat body to the feed and drinking water respectively, or using cotton swabs to dip the bat oral secretions.
Rubbing the nasal cavity of experimental animals;
The remaining one-third, kept in normal cages, served as the control group.
Feed every day, observe the animals every day, write records every day...
Grete was really grateful to Pastor Matthew. He was able to weave cages and build earthen walls. He could catch sheep, pigs, rabbits, and bats with perfect accuracy. He never made a mistake in adding food and water. He could clean the animal cages without getting dirty.
Moving the feed is not too hard. Without his help, this animal experiment could not be completed for a day:
Grete himself tried to catch a rabbit once. He put his hand into the cage and touched it for a minute, but failed to catch it. In the end, he was kicked by the rabbit on the back of his hand. If he hadn't withdrawn his hand quickly, he doubted that his fingers would be able to catch it.
It breaks bones.
Not to mention the stoats that are as fast as lightning, the goats that can gore people, and the black pigs that can weigh at least a hundred kilograms...
Gretel only glanced at it and gave up the idea of taking action.
He stood aside and directed Pastor Matthew: "Grab this rabbit! Turn it upside down! Measure the temperature! Insert the thermometer into your mouth! - Oh, don't insert it into your mouth, I only have one thermometer, don't let it chew it! The mercury
poisonous!"
"…Then where should I insert it?"
Gretel stared into Pastor Matthew's eyes under the beak mask, tightened her lips, and resolutely refused to speak.
And it’s not because of the teacher’s instructions that Pastor Matthew works hard without complaining. In fact, every time he does something, he has countless questions to ask:
"Why do we need to prepare so many kinds of animals?"
"Because I don't know which kind of infection bats can infect." Grete looked at the cage with a look full of pity. So many kinds? I thought I was not prepared enough!
Theoretically, mice, rabbits, dogs, pigeons, as well as pigs, horses and sheep that are known to be intermediate hosts must be prepared. If possible, it would be best to also have civets and pangolins - uh,
Forget about the latter, we are here to protect animals...
"Why feed them the bats with... uh, different stuff?"
"Because we need to determine the route of transmission..." Fecal-oral transmission, droplet transmission, body fluid transmission, different routes require different defense methods. In terms of disease defense, Grete has always shared endless knowledge:
"For example, if you get sick by sneezing from it, you should cover your mouth and nose like we do... If you eat dirty things in your mouth, you must wash your hands before eating..."
"Then why do we need to prepare more than twenty of each kind?"
"Because animal experiments are about betting on probability... Oh, it's about betting on possibility. There are so many animals, and if each method and each type of bat is given one point, there won't be much left."
Twenty is too much?
The little friend next door who specializes in pharmacy told me that whenever a new drug is tested, the first phase of clinical testing will measure the 50% lethal dose or something, and it will start with dozens or hundreds of mice. Note, it is dozens or hundreds of mice, pigeons
Dozens or hundreds of rhesus monkeys...
Oh, rhesus monkeys are precious. All other experimental animals have died. Relatively harmless drugs have been screened out and then tested on rhesus monkeys.
Even when he was studying in his previous life, in order to let clinical medicine students experience the 50% lethal dose experiment, a class would have to be divided into 8 groups, with 6 to 8 mice in each group. After calculation, it would be 48 no matter what.
Only, can you tell whether it is good or bad.
Unlike here, where each transmission route, each type of bat, and the same kind of animal is only divided into two or three. This incredible probability makes him frightened. Whether he can get the result depends purely on his character.
thing.
In other words, is it possible to successfully issue an early warning? Perhaps the national destiny of the Magic Council is at play?
Grete answered without hesitation, and Pastor Matthew kept these unknown knowledge in mind one by one. Even if God knows what it can be used for, it is worth his efforts to help others if they are willing to share it generously.
"Why do you have to have half male and half female again? We have been looking for boars and rams for a long time..." Especially boars. Many young boars were killed and eaten, and breeding pigs are not so easy to borrow. They were just a bag of tears. In the end
As a last resort, I went to the woods to catch a group of wild boars...
“Because of different diseases, the probability of illness in male and female individuals may not be the same…
Alas, poor... Grete looked around the corral, correction, animal laboratory, and cried tears of sympathy for himself in his heart. According to the orthodox experimental design method, doubling the number of experimental animals may not be enough, but...
…
He can hardly afford to support him at this point.
Even if we can afford to raise them, we don’t have the manpower to take care of them. If there are people to take care of them, there aren’t that many manpower to take care of the animals one by one and measure their body temperature...
Alas, no wonder those who make new drugs are all big companies. When his status rises in the future, he will definitely ask the Magic Council for a research team to help him raise experimental animals...
Grete gave himself another reason to work hard to upgrade. Holding a notebook, Pastor Matthew measured the animal's temperature once, and he wrote down something next to it:
"Hare No. 12, body temperature is 39 degrees... Well, let's order two, 39.2 degrees. The food intake is normal, the spirit is normal, the bowel movements are normal, there are no abnormal secretions from the eyes, nose, and mouth, and the health is good... I told you this
Why do we need to measure the rabbit if it’s normal?”
"Then you have to measure it! - Besides, how can you guarantee that it's definitely normal?!"
"I can communicate with it! Even the servants of the God of Nature can do it - right? You can't?!"
"Well……"
Gretel, who is seriously partial to science and sneaks in, Nordmark, except for healing, does not know any other skills of the God of Nature priest...