Tanglou was directly equipped with animal experiment theory (one star, 3), and countless information and materials came into his mind.

Animal experimentation is the most critical and core step in the entire process of new drug research and development, and it is also the bridge for innovation in medicine and technology.

Equipped with the theory of animal experiments, Tanglou began to simulate various animals directly in the laboratory, and soon the common C. elegans, fruit flies, zebrafish, killifish, Xenopus, chickens, rats, and guinea pigs

, hamster, rabbit, tree shrew, pig, cow, buffalo, goat, sheep, ferret, cat, dog, marmoset, crab-eating monkey, macaque, etc.

One after another, very representative animals appeared in the laboratory, and for a moment, the laboratory seemed to have become a zoo.

Among these animals, macaques can be said to be the animals closest to humans within the scope of animal ethics, and are widely used in neuroscience, stem cell science and infectious diseases.

Of course, among these animals, mice are the most widely used, because compared with these animals, mice reproduce quickly, are small, have a docile temperament, and are very easy to raise and breed.

Moreover, among animals that are easier to raise, mice are relatively close to humans and can meet most experimental needs; in addition, mouse cell culture systems, disease models, operating specifications, experimental standards, etc. are among all animals.

They are all the most mature, even more mature than humans themselves.

Tanglou carefully checked the content about mice and was shocked. He seemed to have found the first source of gold for the development of new drugs.

As the most commonly used experimental animal, mice are naturally the experimental animals most in demand by major institutions and scientific research units.

The most stable and widely raised species in China is a kind of white mouse: a variant of the wild mouse, which belongs to the Kingdom Animalia, Phylum Vertebrates, Class Mammalia, Order Rodentia, and Species Rat.

The origins are from the breed introduced from a research institute in India to Kunming, Yunnan Province in 1946. It is also known as Kunming breed and Kunming breed. It is famous in the medical field.

In the 1950s, it was introduced from Kunming to the Beijing Institute of Biological Products and later transported to various parts of the country for breeding.

After people's long-term selection and directional breeding, many varieties have been formed, and there are more than 250 internationally recognized inbred lines.

The so-called "inbred strain", to put it professionally, is to mate the rat cubs with their parents, and then mate the offspring with their grandparents. After more than 20 generations of this cycle, you can screen out a pair with a particularly close genetic background.

The mouse family, this is the concept of inbred lines.

Because the genetic background of inbred strains is similar, as long as two mice belong to the same inbred strain, their experimental results will be consistent, which is very important for biological research that requires strict control of variables.

The morphological characteristics of various inbred strains of mice are slightly different, but they are basically the same. Tanglou discovered that under the experimental animal theory (one star, 3), there is a more optimized inbred strain of ICR mice.

.

The method used to cultivate this kind of optimized mice is also very special, which is to optimize it through the chromosome aberration experiment of Kunbai mice.

The optimized ICR mice have good maternal qualities, a particularly docile temperament, a strong body, and rapid growth. It can be said that the introduction of this kind of mice will inevitably cause a major earthquake in the entire animal experiment world.

Moreover, this chromosome aberration experiment was conducted by administering cyclophosphamide (ide, CP) and colchicine (e, COL) at different time points and at different concentrations to induce chromosome aberrations in mouse bone marrow cells.

The operation process is extremely complex, and as long as it is slightly different, it cannot be successfully induced, which means it is non-replicable and original.

Even to a certain extent, the cultivation and launch of Tanglou's ICR mouse inbred strain has a huge market and profits no less than the launch of hypertension drugs.

As long as it's done properly, it's all money!

Of course, the most important thing is that as long as Tanglou publishes his research, it will definitely cause a huge sensation in the global animal experiment community and gain huge fame and fortune.

However, Tanglou is still in his own virtual laboratory now. What he needs is to start the first batch of cultivation and induction in reality.

Tanglou exited the system space, returned to reality, and began to consider how to carry out his first step plan.

After all, all theories are false. In reality, laboratories, medicines, and tools all require money to implement.

The entire pharmaceutical process, including the synthesis of early-stage compounds, can also be synthesized and prepared through the laboratory of Zijingang Institute of Cardiovascular Diseases.

But the subsequent animal experiments are not that simple. This requires detailed experimental data to support, and huge data requires countless experiments, and the experiments require a lot of manpower and material resources to achieve.

"what to do?"

Tanglou started thinking, and suddenly thought of Mr. Jin Yujin of Jinshi Pharmaceutical in Modu, one of his WeChat friends.

At that time, Jin Yu said that as long as his project was reliable, he would be willing to cooperate with him.

Tanglou thought for a while and without hesitation sent a WeChat message to Jin Yu, roughly explaining that he currently has a research and development project for a new drug for hypertension. It is still in the preparation process, but the basic research and preliminary compound synthesis path have been completed.

The research has even deduced the chemical formula and physical parameters of the core pharmaceutical.

Of course, it is impossible to reveal the specific details of Tanglou to Jin Yu.

Not long after, Mr. Jin wrote back to Tanglou: "Dr. Tang, this matter is not trivial. If you have time, you can come to our company to talk about it."

Of course, Jin Yu's starting point is just to meet Tang Lou to express his gratitude and fulfill his previous cooperation commitment. Of course, the cooperation here is just a formality.

He does not really think that Tanglou can complete the basic research and compound synthesis pathways of hypertension drugs. As for the chemical formula and physical parameters of the core drugs, it is even more fanciful.

With their company's tens of billions of assets, billions of investments every year, and more than a dozen projects, it is already a blessing to have one project progress to the level of chemical formulas and physical parameters.

And Tanglou, a young doctor, how long did it take for him to work under the name of Professor Liu of Zijingang University before he deduced a core sample of a high blood pressure drug?

However, Mr. Jin is not surprised that so many confident young people come to recommend themselves every year and strive for their own investment.

Tanglou thought for a while, and of course he agreed to go to Shanghai to visit Mr. Jin. It only takes more than an hour by train from Hangzhou to Shanghai.

When Tanglou got off at the Shanghai Hongqiao Station, a special driver came to pick him up.

After more than half an hour, Tanglou arrived at King's Pharmaceutical Group.

It has to be said that King Pharmaceuticals is still a very large pharmaceutical company. Of course, it cannot be compared with those top pharmaceutical companies, such as Pfizer, Johnson & Johnson, and Novartis.

King's Pharmaceuticals specially bought land to build a medical valley, which is filled with its industries and various supporting facilities, all of which reveal its wealth.

From the main entrance to the chairman's office and all the way to the tenement building, I was filled with emotion. Since the entire park is a pharmaceutical company, the environment is almost abnormally clean and tidy.

After passing through the entire white-based building complex, the tenement building came to the office building in the center.

Jin Yu met Tang Lou in the grand living room.
Chapter completed!